8 August, 2017
Postdoctoral fellow position available to identify and develop novel treatments for multidrug-resistant Gram negative pathogens (e.g., carbapenem-resistant Enterobacteriaceae). A specific focus of the work would be on development of anti-plasmid agents to restore antimicrobial susceptibility. Work would involve use of high throughput screening approaches; and experiments to optimize antimicrobial properties; define activity spectrum; and delineate mechanism of action. Our goal is to achieve proof of principle for these novel therapeutics and identify candidates for further intensive development.
Several additional antimicrobial discovery and development projects may also be pursued related to blocking pathogen virulence; potentiation of exiting antimicrobials; drug repurposing; and development of next generation antimicrobial susceptibility diagnostics. The laboratory also studies the underlying pathogenic strategies used by several Gram negatives pathogens of major health concern (Legionella, Klebsiella, Brucella, Bartonella).
The Kirby Laboratory is located in Center for Life Science Building in the Harvard Longwood Medical Area, Boston, MA. Academically, we reside within the Experimental Pathology Division of Beth Israel Deaconess Medical Center, a Harvard Medical School-affiliated teaching hospital.
Additional information about the laboratory may be found at: http://kirbylab.org
Candidates must have a PhD or MD/PhD; a background in microbiology; excellent communication skills; and a strong track record of published scientific achievement. Experience with or strong desire to learn how to perform high throughput screening and in vivo infection model experiments is a pre-requisite. Applicants should be achievement oriented, highly motivated, and welcome use of a variety of approaches to address medically important, challenging scientific problems.
To apply for a postdoctoral position and/or to seek additional information, contact James Kirby via email (firstname.lastname@example.org). Please include in one pdf file a C.V.; a statement of career goals; and contact information for three references.
This post is not valid after Friday October 6th, 2017