Postdoctoral Associate, Montclair State University

Postdoctoral Associate, Montclair State University
Postdoctoral Associate, Montclair State University

7 March, 2016

The Talaga Lab at Montclair State University is recruiting for one or more postdoctoral positions.

The postdoctoral research associate will investigate the phenomenon of amyloid formation from ?-synuclein using a variety of biophysical methods, including, but not limited to:
  • Thin Film Circular Dichroism
  • Single Molecule Fluorescence and FRET
  • Protein Expression, Isolation, and Purification
  • Protein Mutagenesis
  • Protein-Dye Conjugation
  • Time-Correlated Single Photon Counting
  • Fluorescence Lifetime Analysis
  • Atomic Force Microscopy
  • Dynamic and Static Light Scattering
  • Neural cell culture
The successful candidate will lead a research team of 4-6 senior undergraduates and graduate students to achieve the following near-term goals:
  1. Elucidate the interfacial contribution to the mechanism of ?-synuclein aggregation:
    • What is the relationship between the nature of the interface and the conformational changes that occur in α-synuclein at those interfaces?
    • Which conformational changes lead to aggregation?
    • What are the aggregation reaction intermediates?
  2. Create a high-sensitivity reporter reagent to detect conformational changes that lead to amyloid-like aggregation.
    • When do conformational changes occur during the aggregation reaction?
    • What cellular components can induce this conformational change?
Salary dependent on experience based on NIH-NRSA scale.
A Ph.D. in , , , or related field is required. Three letters of recommendation are required.

Candidates should send CV and cover letter to

For more information see

This post is not valid after Wednesday April 6th, 2016

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