Postdoctoral Associate, Montclair State University

Postdoctoral Associate, Montclair State University
Postdoctoral Associate, Montclair State University

7 March, 2016

The Talaga Lab at Montclair State University is recruiting for one or more postdoctoral positions.

The postdoctoral research associate will investigate the phenomenon of amyloid formation from ?-synuclein using a variety of biophysical methods, including, but not limited to:
  • Thin Film Circular Dichroism
  • Single Molecule Fluorescence and FRET
  • Protein Expression, Isolation, and Purification
  • Protein Mutagenesis
  • Protein-Dye Conjugation
  • Time-Correlated Single Photon Counting
  • Fluorescence Lifetime Analysis
  • Atomic Force Microscopy
  • Dynamic and Static Light Scattering
  • Neural cell culture
The successful candidate will lead a research team of 4-6 senior undergraduates and graduate students to achieve the following near-term goals:
  1. Elucidate the interfacial contribution to the mechanism of ?-synuclein aggregation:
    • What is the relationship between the nature of the interface and the conformational changes that occur in α-synuclein at those interfaces?
    • Which conformational changes lead to aggregation?
    • What are the aggregation reaction intermediates?
  2. Create a high-sensitivity reporter reagent to detect conformational changes that lead to amyloid-like aggregation.
    • When do conformational changes occur during the aggregation reaction?
    • What cellular components can induce this conformational change?
Salary dependent on experience based on NIH-NRSA scale.
A Ph.D. in , , , or related field is required. Three letters of recommendation are required.

Candidates should send CV and cover letter to postdoc2016@talaga.name

For more information see http://www.talaga.name

This post is not valid after Wednesday April 6th, 2016

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