Bioinformatics in Stem Cell Biology

Bioinformatics in Stem Cell Biology

The Institute for Biomedical , RWTH Aachen University Medical School is offering a position for a

Bioinformatic (PhD Student or ; m/f)

starting as soon as possible. We offer a position, which is initially limited for 2 years with the option for extension. The salary is based on the German public service salary scale (TV-L).

We are analyzing mechanisms of cellular differentiation in various types of stem cells – particularly embryonic stem cells, induced pluripotent stem cells, hematopoetic stem cells, mesenchymal stem cells, and dendritic cells. To this end, we are using own and public datasets that were generated by next generation sequencing (e.g. DNA-Seq, Chip-Seq, RNA-Seq) or microarrays (gene expression arrays and DNA-methylation platforms). The position is for a talented and motivated scientist that interacts closely with Wet-lab scientists of the groups of Prof. Martin Zenke ( and Prof. Wolfgang Wagner ( Particular focus is on epigenetic changes – e.g. histone modifications or DNA-methylation changes during differentiation, disease and aging. The lab will also validate and address bioinformatics hypotheses by genome editing technologies, such as CRISPR/Cas. Furthermore, bioinformatics research will be performed in collaboration with our colleagues at the IZKF Research Group Biology (Dr. Ivan Costa; and the Joined Research Center for Computational Biomedicine at RWTH Aachen University (Professors Andreas Schuppert and Julio Saez-Rodriguez;

We are looking for a motivated and ambitious scientist with a strong background in bioinformatics. You should have at least three years research experience in analysis of NGS data, management of large data, and experience in the programming language R. Basic knowledge in cell biology and stem cell biology would be advantageous as you are expected to understand and contribute to specific scientific questions. You should hold a very good master or PhD degree. Willingness for teamwork is a prerequisite. We offer a highly interactive and well equipped in an international team (all English speaking), with excellent partners, a broad spectrum of methods and a highly relevant research topic.

RWTH Aachen University is certified as a “Family-Friendly University”. We particularly welcome and encourage applications from women, disabled persons and ethnic minority groups, recognizing they are underrepresented across RWTH Aachen University. The principles of fair and open competition apply and appointments will be made on merit.

Please send us your application by E-mail until April 30th 2016 to our secretarial office (E-Mail: Eveline Mierau; It should include a cover letter, which specifically emphasizes your interest in our work (in English), CV with publication list, and copies of the most important certificates.

We are looking forward to your application!

Prof. Dr. Dr. Wolfgang Wagner and Prof. Dr. Martin Zenke

This post is not valid after Saturday April 30th, 2016

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