15 April, 2016
Post Duration: 36 months
Required expertise: PhD (Microbiology/Genetics), Post Doctoral experience in the area of microbial genomics with expertise relevant to the use of bioinformatics to identify potential biocatalysts in bacterial genomes and metagenomes.
Applications are invited for a senior post-doctoral scientist with experience in molecular genetics / bacterial genomics with expertise in bioinformatics to identify and characterize novel biocatalysts from bacterial genomes/metagenomes. The applicant will employ genomics, molecular microbiology and bioinformatics approaches to identify and characterise novel biocatalysts in marine isolates and marine metagenomic libraries constructed from deep sea marine sponges and to subsequent heterologously express these genes in appropriate expression systems. The goal will be to biochemically characterise the recombinant protein for appropriate biocatalytic characteristic with respect to the required industrial application. The research is linked to the group’s on-going strategies based on mining bioactive compounds from marine organisms to develop novel antimicrobial as effective therapeutic agents for clinical /industrial applications.
The recruited scientist will be based in the Environmental Microbiology group, headed up by Professor Alan Dobson, within the School of Microbiology; with research links to the BIOMERIT Research Centre (http://www.ucc.ie/en/biomerit/) at University College Cork. The group’s main area of interest is in the study of microorganisms in marine and terrestrial environments and their potential biotechnological exploitation. They focus on gaining a fuller understanding of how microbes survive, grow and interact in their various ecological niches; an approach which is fundamental to their biotechnological applications. The researchers have an established international track record in microbial and fungal genetics, microbial biodiversity and in marine biodiscovery. In the context of this project novel biocatalysts of industrial importance are being targeted, as part of the Synthesis and Solid State Pharmaceutical Centre (SSPC), a Global Hub of Pharmaceutical Process Innovation and Advanced Manufacturing, funded by Science Foundation Ireland and industry, 9 research performing organisations and 12 international academic collaborators http://www.sspc.ie/. The SSPC leads the way for next generation drug manufacture and spans the entire pharmaceutical production chain from synthesis of the molecule, to the isolation of the material, and the formulation of the medicine. The aim of the SSPC is to deliver industry relevant solutions, which result in job growth and retention within the pharmaceutical industry in Ireland.
This is an advanced research training role, allowing the applicant to build on their prior experience as a Post-Doctoral, where you will conduct a specified programme of research and research training under the guidance of a Principal Investigator. The primary purpose of the role is to deliver research results and objectives, develop new and advanced research skills and competencies; the successful development of funding proposals and to interact in the supervision and mentorship of graduate students, in conjunction with an academic supervisor. The individual will also be expected to make major scientific contributions to the research goals of the group in the marine biotechnology discovery area.
For Informal Enquiries please contact:
Please submit a short cover letter and C.V. to Professor Alan Dobson on or before the closing date May 13th, 2016.
Supplementary Information on the School of Microbiology and the post is available at the following URL: http://www.ucc.ie/en/microbiology/
This post is not valid after Friday May 13th, 2016