Calculation of statistical significance for Fis index

Calculation of statistical significance for Fis index

22 December, 2012

Dear all,

I have a huge SNP dataset (hundreds of individuals and about 50K markers) including several populations. I need to calculate the value of the Fis (inbreeding coefficient) index for each population, including the level of statistical significance of the index value.

The software and scripts I found so far only return the index value but no statistical significance.

Does anyone know a package, R script or algorithm able to do this?

Thank you in advance.

Licia Colli

Licia Colli, PhD
Istituto di Zootecnica – Facolt di Agraria
Universit Cattolica del S. Cuore
via Emilia Parmense, 84
29122 Piacenza (PC)

e-mail: licia.colli@unicatt.it
skype: liquid-diamond
Tel: +39 – 0523599205
Fax: +39 – 0523599276

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